Circulating Serum 25-Hydroxyvitamin D Levels and Bone Mineral Density: Mendelian Randomization Study
نویسندگان
چکیده
منابع مشابه
Association between serum 25-hydroxyvitamin d levels, bone geometry, and bone mineral density in healthy older adults.
PURPOSE The association between serum 25-hydroxyvitamin D values and cortical/trabecular bone parameters in older adults has been incompletely explored. This study was designed to investigate the relationship between serum 25-hydroxyvitamin D levels and bone parameters for the tibia and radius using peripheral quantitative computed tomography in free-living healthy older adults. METHODS The s...
متن کاملMammographic density and serum 25-hydroxyvitamin D levels
BACKGROUND Vitamin D, which influences cellular proliferation and breast tissue characteristics, has been inversely correlated with breast cancer risk. Dietary vitamin D intake has been associated with lower mammographic density (MD), a strong intermediate marker of breast cancer risk. FINDINGS We examined the relationship between MD and serum 25-hydroxyvitamin D [25(OH)D], an integrated meas...
متن کاملRelation of serum 25 hydroxyvitamin D levels to bone mineral density in southern Chinese postmenopausal women: A preliminary study
BACKGROUND & OBJECTIVES Vitamin D insufficiency is prevalent in postmenopausal women and has been related to low bone mineral density (BMD). However, controversial results have been reported for the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and BMD. This study was done to investigate whether serum 25(OH)D levels were associated with BMD in postmenopausal women living in Gu...
متن کاملHip Fractures and Bone Mineral Density in the Elderly—Importance of Serum 25-Hydroxyvitamin D
BACKGROUND The significance of serum 25-hydroxyvitamin D [25(OH)D] concentrations for hip fracture risk of the elderly is still uncertain. Difficulties reaching both frail and healthy elderly people in randomized controlled trials or large cohort studies may in part explain discordant findings. We determined hazard ratios for hip fractures of elderly men and women related to serum 25(OH)D, incl...
متن کاملThe seasonal importance of serum 25-hydroxyvitamin D for bone mineral density in older women.
BACKGROUND The impact of season when determining a serum 25-hydroxyvitamin D (S-25OHD) cut-off level for optimal bone health is unknown. OBJECTIVE To investigate the relative importance of S-25OHD for bone mineral density (BMD) by season. METHODS A subcohort of 5002 Swedish women (mean age 68 years), randomly selected from a large population-based longitudinal cohort study with repeat dieta...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2018
ISSN: 0884-0431
DOI: 10.1002/jbmr.3389